Alzheimer’s disease represents one of the most challenging neurodegenerative disorders of our time, exacting a profound emotional and economic toll on patients, families, and healthcare systems worldwide. The condition’s hallmark, a relentless cognitive decline and memory loss, often falls under the purview of caretakers who assume the responsibility of not only managing the day-to-day needs but also interpreting and communicating the subjective cognitive decline (SCD) of patients. Recent findings published in the Journal of the National Medical Association present a comprehensive analysis of how this decline might be perceived differently across racial lines, underpinning the urgent need for equality-driven healthcare approaches. This article offers an exhaustive look into this critical work and the ramifications of its insights.

Research Overview and Methodology

In the study authored by Wang et al. (2024), titled “Racial disparities in subjective cognitive decline and its implications among Alzheimer’s caretakers,” researchers mined data from the CDC’s Alzheimer’s Disease and Healthy Aging Data Portal, focusing on reports from 12,627 Alzheimer’s caretakers. They used advanced statistical tools like JMP software to conduct fit model tests and distribution analyses, as they sought to quantify disparities in symptom severity across different racial groups including Asian/Pacific Islander, Black, Hispanic, Native American/Native Alaskan, and White patients.

The investigation probed four key areas:
1. Daily functional decline.
2. Communication difficulties.
3. Memory impairment.
4. Executive function deficits.

These areas were essential in evaluating how caregivers perceive and report the extent of symptoms experienced by Alzheimer’s patients.


The study’s findings were telling: there are significant racial disparities in how subjective cognitive decline is reported by Alzheimer’s caretakers, with Hispanic, Native American/Native Alaskan, and Black patients seemingly experiencing the most severe symptoms. Conversely, White and Asian/Pacific Islander patients had the least severe symptoms reported by their caretakers. Crucially, disparities also emerged in communication with healthcare providers, with the Asian population having the least interaction rates.

This communication gap is vital, as it has implications for treatment, intervention, and support for both patients and caretakers. The authors highlight that cultural, socioeconomic, and potentially genetic factors contribute to these variances, calling for a more tailored approach when it comes to interventions and caregiving support.

Implications and Recommendations

The implications of such disparities are far-reaching. From diagnosis to treatment and support, racial differences in the perception of symptoms can impact the quality of care received by Alzheimer’s patients. The study recommends targeted interventions that take into account cultural nuances and specific needs, emphasizing on:
1. Enhanced caregiver education emphasizing on cultural competence.
2. Better access to support services for minority populations.
3. Improved communication strategies between healthcare providers and caretakers from underrepresented communities.

Further Discussions

Amid these revelations, healthcare policies must incline towards inclusivity and equity. Alzheimer’s disease does not discriminate, but barriers in healthcare access and cultural stigmatization can inadvertently favor or disfavor racial groups. As the paper suggests, understanding the unique experiences of Alzheimer’s patients and their caretakers across racial lines is pivotal to devising effective, humane responses to the crisis.


1. Wang, D. D., Mangal, R. K., Daniel, A. A., Gould, M. M., Stead, T. S., & Ganti, L. (2024). Racial disparities in subjective cognitive decline and its implications among Alzheimer’s caretakers. Journal of the National Medical Association, S0027-9684(24)00003-8.
2. Alzheimer’s Association. (2021). 2021 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia, 17(3), 327-406.
3. Yaffe, K., Falvey, C., & Harris, T. B. (2014). Effect of socioeconomic disparities on incidence of dementia among biracial older adults: prospective study. BMJ, 349, g7051.
4. ChinAlzheimer’s and Related Disorders Society. (2016). Alzheimer Disease in African Americans: Risk Factors and Challenges for the Future. Health Affairs, 35(8), 1533-1538.
5. Brewster, P. W., Melrose, R. J., Marquine, M. J., Johnson, J. K., Napoles, A., MacKay-Brandt, A., Farias, S., Reed, B., & Mungas, D. (2015). Life experience and demographic influences on cognitive function in older adults. Neuropsychology, 29(6), 846-858.


1. Alzheimer’s Racial Disparities
2. Caregivers Cognitive Decline
3. Alzheimer’s Disease Communication
4. Targeted Alzheimer’s Interventions
5. Alzheimer’s Healthcare Equity


The pioneering research by Wang et al. serves as both a clarion call and a roadmap for the restructuring of Alzheimer’s care—a plea for the eradication of racial inequities and the promotion of personalized care strategies. The role of caretakers, equipped with better education and support, becomes central in this transformation, as it is only through their informed observations that the nuanced symptoms of Alzheimer’s can be accurately conveyed and treated. And while the work sets forth a clearer picture of the racial disparities that permeate Alzheimer’s care, it doubles as a foundation for actionable policies, aimed at ensuring that the most vulnerable can access the standard of care they rightfully deserve.