In a significant case reported within the realm of medical imaging, researchers at the Cardinal Stefan Wyszyński Institute of Cardiology in Warsaw, Poland, stumbled upon an incidental finding that underscores the unpredictability and depth of investigative imaging techniques. The case, documented in the May 2019 issue of ‘Circulation: Cardiovascular Imaging’, a journal of the American Heart Association, describes the unexpected detection of bilateral breast tumors during scintigraphic myocardial perfusion imaging. The remarkable finding draws attention to the potential for incidental diagnoses that extend beyond the primary focus of cardiovascular assessments, carrying implications for the scope of patient care and the cross-specialty alertness required by clinicians.

DOI: 10.1161/CIRCIMAGING.118.008728

Incidental Finding – A Diagnostic Surprise

The patient, an aged female, underwent myocardial perfusion imaging—an advanced nuclear medicine scan that visualizes the blood flow to the heart muscles—to evaluate coronary stenosis, a condition characterized by the narrowing of the coronary arteries. Yet, what began as a routine cardiac assessment rapidly transitioned into an oncological concern. The imaging unexpectedly revealed the presence of bilateral breast tumors.

The Implications of Incidental Findings

Incidental findings in medical imaging are discoveries that are unrelated to the original diagnostic query. While sometimes clinically negligible, they can also be revelatory, unveiling conditions that might otherwise remain undetected until they present with more severe symptoms or at a more advanced stage. Although incidental findings can lead to early and potentially life-saving interventions, they also pose challenges, such as the psychological impact on patients, additional diagnostic tests, and potential overtreatment.

The Details of the Case

The case report, authored by Marek Cacko, Anna Teresińska, Jacek Omyła, Mariusz Dębski, and Wojciech Cytawa, details the clinical pathway followed after the discovery of the breast tumors. Further investigations, which included ultrasonography and mammography, confirmed the existence of carcinoma—specifically, ductal and lobular carcinoma, two common types of breast cancer. The tumors were surgically removed via mastectomy, illustrating how an incidental finding in cardiovascular imaging led to the identification and treatment of a critical non-cardiac condition.

The Role of Myocardial Perfusion Imaging

Myocardial perfusion imaging (MPI) is typically employed to investigate coronary artery disease and the risk of heart attacks. MPI is a form of radionuclide imaging that is sensitive enough to detect abnormalities in blood flow or identify areas of the heart muscle that have suffered damage. The imaging technique, therefore, holds predictive value for cardiac events but is not predominantly aimed at detecting other pathologies, such as tumors.

Advancements in Imaging Technology

The unexpected discovery in this case is, in part, a testament to the advancements in imaging technology. Modern scintigraphic imaging, as utilized in MPI, has increased resolution and sensitivity, making it possible to detect incidental abnormalities. It is likely that as imaging techniques continue to improve, the frequency of incidental findings will rise, prompting the medical community to refine the approaches to managing these discoveries.

The Significance of Interdisciplinary Collaboration

This case underlines the importance of interdisciplinary collaboration in healthcare. The incidental finding of breast tumors during cardiac imaging required an integrated response involving cardiologists, oncologists, and radiologists, leading to effective diagnosis and treatment. The convergence of cardiology and oncology in this scenario exemplifies the necessity of cross-specialty vigilance and the benefits it can bring to patient outcomes.

Educational and Ethical Considerations

Clinicians and researchers must be educated about the possibility and implications of incidental findings to prepare for and manage such scenarios effectively. The ethical considerations — such as informing patients about the potential for incidental discoveries, the subsequent steps, and the psychological support systems needed — are equally vital.


The incidental finding of bilateral breast tumors during a scintigraphic myocardial perfusion imaging procedure adds an important chapter to the growing anthology of case studies that reflect the serendipitous achievements and challenges of modern medical imaging. As technology continues to evolve, the medical community must stay vigilant, ensuring that these incidental findings are leveraged to enhance patient care without causing undue harm or distress.


1. Cacko, M., Teresińska, A., Omyła, J., Dębski, M., & Cytawa, W. (2019). Incidental Finding of Bilateral Breast Tumor in Scintigraphic Myocardial Perfusion Imaging. Circulation: Cardiovascular Imaging, 12(5), e008728.

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4. Brenner, D. J., & Hall, E. J. (2007). Computed tomography — an increasing source of radiation exposure. The New England Journal of Medicine, 357(22), 2277-2284.

5. Lumbreras, B., Donat, L., & Hernández-Aguado, I. (2010). Incidental findings in imaging diagnostic tests: A systematic review. British Journal of Radiology, 83(988), 276-289.


1. Myocardial Perfusion Imaging Incidental Findings
2. Bilateral Breast Tumors Detection
3. Cardiac Imaging Breast Cancer
4. Radiological Incidental Discovery
5. Scintigraphic Imaging Advancements