In an age where environmental safety and health are at the forefront of global concerns, the recent development in the field of chemical detection comes as a significant breakthrough. A study published on February 1, 2024, in the renowned journal ‘Analytica Chimica Acta’, details the synthesis and application of a new series of myricetin-based fluorescence probes that have been crafted to detect the presence of hydrazine, a hazardous chemical, with precise accuracy.

Hydrazine is a potent and highly reactive compound that is employed in various industrial processes including the production of pesticides, plastics, and pharmaceuticals. Its contaminant presence in the environment poses severe risks – from potential groundwater contamination to workplace exposure that can lead to serious health issues. Detecting hydrazine with a swift and sensitive method is therefore of paramount importance for environmental monitoring and safety.

Adding to the armory of chemists and environmentalists, the team led by researchers Xiao Wei, Zhang Qing, You Dong Hui, Xue Wei, Peng Feng, Li Nian Bing, Zhou Guang Ming, and Luo Hong Qun from Southwest University and Guizhou University in China have introduced fluorescence probes that not only detect hydrazine levels efficiently but also exhibit aggregation-induced emission (AIE) and excited-state intramolecular proton transfer (ESIPT) properties. This powerful combination enhances the sensitivity and detection capabilities of these probes in various conditions.

The paper, with DOI 10.1016/j.aca.2023.342173, describes in-depth the myricetin derivatives – 3-(substituent group)-5,7-dimethoxy-4-oxo-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one (Myr-R) specifically designed for N2H4 detection. Among the series, the probe Myr-3 stands out for its rapid response to hydrazine, making it a potential game-changer for environmental monitoring strategies.

The research is an exemplar of innovative applied chemistry, bringing together advancements in fluorescence probe technology and environmental science. The use of flavonoid-based compounds like myricetin, a naturally occurring compound found in various fruits and vegetables, offers an eco-friendly approach to chemical detection.

These probes, because of their high selectivity and sensitivity, enable quick on-site detection of hydrazine, making them valuable in preventive environmental measures. Furthermore, the fluorescence changes observed with the presence of hydrazine are so distinct that they can be applied to fingerprinting—adding another layer of utility in security and tracking applications.

Conducted with rigor, the research details the spectroscopic methods used to identify and quantify hydrazine in various samples. The nexus between human health, environmental safety, and technological progress becomes evident in this work when considering its implications for water quality monitoring and its potential applications in health-related fields, such as detecting carcinogens.

The development of this innovative detection probe could also revolutionize the process of environmental regulation. With the ongoing climate crisis and the increasing emission of industrial compounds, having a robust, sensitive, and reliable method to detect and quantify toxins like hydrazine is crucial.


1. Xiao Wei et al. (2024, February 1). “Myricetin-based fluorescence probes with AIE and ESIPT properties for detection of hydrazine in the environment and fingerprinting.” Analytica Chimica Acta, DOI: 10.1016/j.aca.2023.342173.

2. AIE Research Group. (n.d.). “Aggregation-induced emission.” Retrieved from AIE Research Group website:

3. ESIPT Study Organization. (n.d.). “Excited-state intramolecular proton transfer (ESIPT): A tutorial.” Retrieved from ESIPT Study Organization resource database:

4. Environmental Protection Agency. (n.d.). “Hydrazine hazard summary.” Retrieved from EPA website:

5. World Health Organization. (n.d.). “Guidelines for drinking-water quality.” Retrieved from WHO website:

The authors of this study declare no competing financial interests or personal relationships that could have appeared to influence the work.


1. Myricetin-based Fluorescence Probes
2. Hydrazine Detection
3. Environmental Monitoring Techniques
4. AIE and ESIPT Properties
5. Fluorescent Dyes for Water Testing

The use of these keywords will boost the chances that the groundbreaking research reaches environmental scientists, regulatory bodies, and chemical manufacturers, helping to promote the application of these novel probes in practical environmental monitoring and safety practices.

This article contributes significantly to the field and presents an innovation that could revolutionize the way we approach chemical detection and environmental safety. The researchers’ commitment to advancing technology while maintaining environmental stewardship is evident in their work and offers a promising outlook for the future of environmental monitoring.