A significant breakthrough in environmental monitoring has emerged with the development of advanced materials known as carbon dots (CDs), capable of seeking out potential hazards like ultraviolet (UV) light and harmful bacteria. Published in “Analytica Chimica Acta” on February 1st, 2024 (DOI: 10.1016/j.aca.2023.342140), a team of researchers—including Zhao Dan, Liu Huan, Zhang Changpeng, Xiao Xincai from the School of Pharmaceutical Sciences, South-Central Minzu University, and He Zhike from the College of Chemistry and Molecular Sciences, Wuhan University—reveals the innovative use of CD nanozymes in environmental safety applications.

UV radiation and foodborne pathogenic bacteria, such as Escherichia coli (E. coli) O157:H7, are known to pose severe threats to human health and the broader ecosystem. Effective detection mechanisms are pivotal in preventing disease outbreaks and ensuring public health security. The discovery detailed in the study signifies a remarkable advancement in both UV monitoring and bacterial typing, which could revolutionize how we protect our environment and ourselves.

Carbon Dots: A Primer to Nanozymes

Nanozymes are nanomaterials with enzyme-like properties. Carbon dots are emerging as a fascinating subclass of nanozymes due to their unique characteristics, including high stability, tunable fluorescence, and versatile catalytic activities. In the reported research, CDs with the dual enzyme-like activities of superoxide dismutase and UV-induced oxidase were synthesized. These CDs exhibited a strong capability to catalyze the oxidation of the substrate 3, 3′, 5, 5′-tetramethylbenzidine (TMB) upon exposure to UV light (365 nm), inducing rapid color development.

Dual-Channel Real-Time Detection of UVA Dosage

This study introduced a groundbreaking approach to measuring UVA doses by harnessing the fluorescence properties of the CDs. A colorimetric-fluorescence dual-channel real-time detection system was constructed, providing a quick and accurate assessment of UVA exposure, which is crucial in numerous industrial and environmental scenarios.

UV Monitoring Innovations with Smartphone Integration

Progressing further, the researchers developed a portable CDs-TMB-PA hydrogel. This innovative hydrogel enables real-time monitoring of UV in outdoor settings with a simple yet highly effective addition: smartphone connectivity. This accessibility positions the technology for widespread adoption and use by everyday consumers, as well as professional environmental agencies.

Pathogen Detection: Fast and Sensitive Bacterial Typing

Especially noteworthy is the application of CD nanozymes in the detection and typing of pathogen strains such as E. coli O157:H7. By leveraging the pH-dependent properties of the CDs and the specific glycolytic response of E. coli O157:H7, a rapid, straightforward, and highly sensitive method was developed for bacterial identification. Such technology offers immense promise in food safety and healthcare, providing fast detection that could prevent the spread of infectious diseases.

Implications for Public Health and Environmental Monitoring

The research’s implications are vast, offering new vistas in the study of CD nanozymes. Not only do these advancements present practical applications for real-time UV and bacterial detection, but they also signify a notable leap in our ability to combat environmental hazards. This technology has the potential to become an integral component of public health initiatives, industrial safety protocols, and environmental conservation efforts.

Copyright Notice and Competing Interests

Copyright © 2023 Elsevier B.V. All rights reserved. The authors, who performed this research, declared no conflicts of interest, as noted in the publication, ensuring the integrity of their scientific work.


1. Carbon Dot Nanozymes
2. UVA Detection Technology
3. Escherichia coli O157:H7 Detection
4. Environmental Monitoring Innovations
5. Photocatalytic Bacterial Typing


1. Zhao, D., Liu, H., Zhang, C., Xiao, X., & He, Z. (2024). UV-induced oxidase activity of carbon dots in visible UVA dosage, Escherichia coli quantification and bacterial typing. Analytica Chimica Acta, 1288, 342140. https://doi.org/10.1016/j.aca.2023.342140
2. Liu, Y., et al. (2022). Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications. Chemical Reviews, 121(8), 5069–5129. https://doi.org/10.1021/acs.chemrev.0c01327
3. Zhang, M., et al. (2021). Advancements in carbon dot-based fluorescent probes for bioimaging applications. Materials Today, 41, 89-112. https://doi.org/10.1016/j.mattod.2020.07.020
4. Wang, S., et al. (2023). Carbon dots for environmental monitoring: A review on optical sensors and bioimaging. Sensors and Actuators B: Chemical, 364, 132131. https://doi.org/10.1016/j.snb.2022.132131
5. Huang, H., et al. (2021). A portable smartphone-based platform for highly sensitive fluorescence detection of pathogenic bacteria. Talanta, 233, 122435. https://doi.org/10.1016/j.talanta.2021.122435


The quest for developing robust, sensitive, and user-friendly environmental monitoring systems has made a significant stride forward with the introduction of CD nanozymes exhibiting dual enzyme-like activities. This research reflects a milestone in interdisciplinary collaboration, seamlessly blending chemistry, microbiology, and materials science to create solutions that address urgent environmental and public health concerns. As we continue to grapple with the challenges posed by UV radiation and bacterial contamination, this technology stands out as a beacon of innovation, equipping society with the means to detect and respond to these threats more effectively than ever.